The laboratory for centrosome and cytoskeleton biology

Centrosomes and cilia in brain development and cancer

NEWS!!

A new review paper

Trends and challenges in modeling glioma using 3D human brain organoids.

By Arul&Co on summarizing human brain organoids in modeling glioma is out in

-Cell Death Differentiation.

Wonderful collaborative work with the Soren lab linking unexpected function of RRP7A in microcephaly development.

-Nature Communication

 

SARS‐CoV‐2 targets neurons of 3D human brain organoids

 

Our new work is out in the EMBO Journal!!

https://www.embopress.org/doi/10.15252/embj.2020106230

Also see the press release

https://www.embo.org/news/press-releases/2020/mini-brain-organoids-show-potential-for-sars-cov2-to-cause-neurodegenerative-disease-like-effects.html

 

Patient-derived glioma stem cells (red) interact and integrate with outgrowing neurons (green) of organoids