The laboratory for centrosome and cytoskeleton biology

Institute of Human Genetics and Leibniz Research Institute for Environmental Medicine (IUF) Heinrich-Heine-Universität Düsseldorf, Germany.

Centrosomes and cilia in brain development and cancer


1. New paper in EMBO Journal!!

Our dream work is now in EMBO Journal!! Congratulations to Dr. Arul and thanks to the reviewers!!

This work identifies CCB02, a novel tubulin binder that inhibits CPAP-Tubulin interaction to activate centrosomes.

CCB02 activates extra centrosomes, prevents centrosomes clustering and specifically kills cancer cells with extra centrosomes.


This work thus additionally supports that extra centrosomes can be targeted for potential cancer therapeutics !!

Contact us for CCB02.